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BIO-ENCAPSULATION
SCIENCE
The definition of micro-encapsulation in the literature is used for micro-capsules with different properties. One could define two mainstreams : core/shell particles and matrix pellets. One of the first industrial processes was the carbonless self copying paper : micro capsules filled with ink are fixed on the back side of the paper and crushed by the pencil when writing on the paper.
There are numerous reasons for micro-encapsulation. Consequently there are many compositions and a handful of processes. A process for encapsulation of powders is in general different from the process for liquids.
Bio-encapsulation is the definition used for micro and nano encapsulation of bioactive substances. One of the examples is micro-encapsulated marine oils, which combines unpleasant flavor with instability and being available as a liquid dosage form only.
Bio-encapsulation is the definition used for micro and nano encapsulation of bioactive substances. One of the examples is micro-encapsulated marine oils, which combines unpleasant flavor with instability and being available as a liquid dosage form only.
The keywords to all forms of core/shell bio-encapsulation are protection and controlled release. |
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Much scientific work is done worldwide to encapsulate living cells, such as Langerhans cells, which would allow the implantation and stabilization within the human body. Bio-active compounds are by definition chemically and physically active, their reaction might not always be compatible with the environmental conditions, for example enzymes may loose their functionality when exposed to heat. Bio-encapsulation can protect them in the palletizing process.
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